Pulmonary defence mechanisms and inflammatory pathways in bronchiectasis
نویسندگان
چکیده
Over recent years there has been a tremendous increase in the understanding of pulmonary immunity, mostly driven by large research efforts in understanding the basis of asthma and chronic obstructive pulmonary disease. Bronchiectasis is well understood. In this article, an overview of pulmonary defence mechanisms as well as inflammatory mechanisms is given as a basis to understand the pathogenesis of bronchiectasis.
منابع مشابه
Giant Endobronchial Inflammatory Polyp
Inflammatory endobronchial polyp is a rare disease mostly encountered in asthmatic patients. Chronic airway and foreign material irritation or thermal injury may result in the formation of granulated tissues and become polypoid mass. Herein, we describe a 52-year-old man with severe respiratory distress and infection with 35 years history of smoking. He had an obstructive pattern in his pulmona...
متن کاملDifferential expression of inflammatory responsive genes between chronic periodontitis and periodontally affected bronchiectasis patients
The study aimed to investigate differential expression of targeted inflammatory-immune responsive genes [LTA, LTB, TNFSF4, TNFSF11/RANKL, TNFSF13, TNFSF13B, TNFRSF11B/ Osteoprotegerin; OPG and GFPT1/GFA ] in gingival tissues of bronchiectasis patients having chronic periodontitis in North central Indian population. Gingival tissues were collected from 30 systemically healthy chronic periodontit...
متن کاملAnalysis of the Sputum and Inflammatory Alterations of the Airways in Patients with Common Variable Immunodeficiency and Bronchiectasis
INTRODUCTION Common variable immunodeficiency is characterized by defective antibody production and recurrent pulmonary infections. Intravenous immunoglobulin is the treatment of choice, but the effects of Intravenous immunoglobulin on pulmonary defense mechanisms are poorly understood. OBJECTIVE The aim of this study was to verify the impact of intravenous immunoglobulin on the physical prop...
متن کامل[Transport of mucoid mucus in healthy individuals and patients with chronic obstructive pulmonary disease and bronchiectasis].
OBJECTIVE To characterise and compare the in vitro transport properties of respiratory mucoid secretion in individuals with no lung disease and in stable patients with chronic obstructive pulmonary disease (COPD) and bronchiectasis. METHODOLOGY Samples of mucus were collected, from 21 volunteers presenting no lung disease who had undergone surgery, from 10 patients presenting chronic COPD, an...
متن کاملThe significance of localized bronchiectasis adjacent to pulmonary coin lesions.
In an effortto determine potential diagnostic usefulness of bronchiectasis adjacent to pulmonary coin lesions, 39 cases were evaluated by chest roentgenogram and bronchography. Ten of 17 benign lesions demonstrated localized adjacent bronchiectasis. Twenty-one of 22 malignant coin lesions failed to demonstrate that finding. Localized bronchiectasis adjacent to a “coin lesion” is a useful indica...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2011